Seretide Evohaler 250mcg is a combination medication containing fluticasone propionate and salmeterol. Fluticasone is a corticosteroid that reduces inflammation in the airways, while salmeterol is a long-acting beta agonist that helps relax the muscles around the airways. This combination works by reducing inflammation and opening the airways, making it easier to breathe. It is used as a maintenance treatment for asthma and chronic obstructive pulmonary disease (COPD) in patients who require both a corticosteroid and a long-acting beta agonist.